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Mississippi State Department of Health Ensures Naloxone is Readily Available

Prescriptions not necessary to obtain lifesaving opioid reversal medication


As part of continued efforts to reduce overdose deaths, the Mississippi State Department of Health (MSDH) has extended and expanded the statewide naloxone standing order that permits pharmacists to dispense the opioid reversal medication naloxone without a prescription from doctors or other medical practitioners.


According to MSDH, overdoses are now the leading cause of death among U.S. adults 18-45.


Naloxone blocks the brain’s opioid receptors and restores normal breathing in people who have overdosed on fentanyl, heroin or prescription opioid painkillers. Naloxone’s temporary blocking effect allows time for professional medical attention to be sought.


“Since this order was originally issued in 2018, many lives have been saved in communities throughout Mississippi because of the expanded availability of naloxone,” said Jan Dawson, program director, Mississippi Public Health Institute. “We applaud our partners at the Mississippi State Department of Health for extending the order and for expanding it to include products that were not previously covered by the standing order, and to removing barriers to obtaining this lifesaving drug.”


Signed by State Epidemiologist Dr. Paul Byers, the standing order states that pharmacists are allowed “to dispense an opioid antagonist [naloxone] to a person at risk of experiencing an opioid-related overdose or to a family member, friend or other person in a position to assist an at-risk person.” And according to Mississippi’s Medical Emergency Good Samaritan Act, one cannot be prosecuted for calling 911 in the event of an overdose—even if they are in possession of a drug.


The Centers for Disease Control and Prevention estimates that more than 106,000 people died in the U.S. as the result of a drug overdose in the 12-month period ending November 2021, with opioid-related deaths accounting for 75% of all overdose deaths. A report from the Mississippi Opioid and Heroin Data Collaborative showed that drug overdose deaths in Mississippi rose by 49% in one year from 2019-2020.


Make Mississippi OD Free is a program administered by the Mississippi Department of Health in partnership with the Mississippi Public Health Institute, and is supported by a federal grant initiative funded by the Centers for Disease Control and Prevention. is an online news source serving Simpson and surrounding counties as well as the State of Mississippi.

How does naloxone work and how do you use it?

Naloxone quickly reverses an overdose by blocking the effects of opioids. It can restore normal breathing within 2 to 3 minutes2 in a person whose breath has slowed, or even stopped, as a result of opioid overdose. More than one dose of naloxone may be required when stronger opioids like fentanyl are involved.3

Naloxone is easy to use and light to carry. There are three forms of naloxone that anyone can use without medical training or authorization: nasal spray, auto-injector, and injectable.

If you give someone naloxone, stay with them until emergency help arrives or for at least four hours to make sure their breathing returns to normal.3    (CDC)


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